makes some people appear astonishingly youthful while others seem much older than their ac

makes some people appear astonishingly youthful while others seem much older than their actual age?
A. What it is
B. What is it that
C. What it is that
D. Why it is what

A. What it isB. What is it thatC. What it is thatD. Why it is what解析： 考查强调结构的特殊疑问句。句意为：究竟为什么有些人会看起来年轻得让人吃惊，而另一些人却看起来比实际年龄苍老得多？题干缺少主语，因此如果句首只填一个词时应填what,变为强调结构的特殊疑问句则是What is it that...。

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