his knowledge of the mountainous country, John Smith was appointed as our guide.A. In spi

his knowledge of the mountainous country, John Smith was appointed as our guide.
A. In spite of
B. On account of
C. Regardless of
D. Instead of

A. In spite of(答案→)B. On account of C. Regardless ofD. Instead of解析：　　on account of(=because of)由于，因为。regardless of(=without worrying about)不顾；Regardless of danger, he climbed the tower.

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